{"id":88591,"date":"2026-05-08T12:45:49","date_gmt":"2026-05-08T16:45:49","guid":{"rendered":"https:\/\/www.mundoacuicola.cl\/new\/?p=88591"},"modified":"2026-05-08T12:46:10","modified_gmt":"2026-05-08T16:46:10","slug":"estudio-identifica-peptidos-de-microalgas-contra-patogenos-del-salmon","status":"publish","type":"post","link":"https:\/\/www.mundoacuicola.cl\/new\/estudio-identifica-peptidos-de-microalgas-contra-patogenos-del-salmon\/","title":{"rendered":"Estudio identifica p\u00e9ptidos de microalgas contra pat\u00f3genos del salm\u00f3n"},"content":{"rendered":"

Un estudio cient\u00edfico identific\u00f3 nuevos p\u00e9ptidos antibacterianos obtenidos a partir de la microalga Chlamydomonas reinhardtii<\/em>, compuestos que mostraron actividad contra pat\u00f3genos relevantes para la salmonicultura y que podr\u00edan contribuir al desarrollo de alternativas m\u00e1s sostenibles al uso de antibi\u00f3ticos convencionales en acuicultura.<\/p>\n

La investigaci\u00f3n fue desarrollada por el Laboratorio de Gen\u00e9tica e Inmunolog\u00eda Molecular y el N\u00facleo Biotecnolog\u00eda Curauma de la Pontificia Universidad Cat\u00f3lica de Valpara\u00edso (PUCV), con la participaci\u00f3n de la doctora Pabla Ugalde, quien lider\u00f3 el estudio en el marco de su investigaci\u00f3n doctoral en biotecnolog\u00eda de microalgas y acuicultura.<\/p>\n

Seg\u00fan explic\u00f3 Ugalde, el trabajo se enfoc\u00f3 en el desarrollo de alternativas innovadoras y sostenibles al uso de antibi\u00f3ticos convencionales para el control de pat\u00f3genos que afectan la producci\u00f3n de salmones, integrando ciencia aplicada, biotecnolog\u00eda y salud acu\u00edcola.<\/p>\n

La investigaci\u00f3n<\/strong><\/h3>\n

Publicado en Algal Research<\/em>, el estudio evalu\u00f3 tres microalgas verdes mediante procesos de hidr\u00f3lisis enzim\u00e1tica para identificar compuestos con potencial antibacteriano. Entre ellas, Chlamydomonas reinhardtii<\/em> present\u00f3 la mayor actividad inhibitoria frente a Vibrio anguillarum<\/em> y Piscirickettsia salmonis<\/em>, agentes asociados a vibriosis y septicemia rickettsial del salm\u00f3n (SRS), respectivamente.<\/p>\n

Los investigadores identificaron diez secuencias pept\u00eddicas derivadas de esta microalga y sintetizaron qu\u00edmicamente aquellas con mayor potencial antimicrobiano. Tres de estos p\u00e9ptidos mostraron actividad inhibitoria frente a distintas bacterias, mientras que la combinaci\u00f3n de dos de ellos permiti\u00f3 reducir significativamente la concentraci\u00f3n necesaria para inhibir el crecimiento de Vibrio anguillarum<\/em>, evidenciando un efecto sin\u00e9rgico.<\/p>\n

El trabajo tambi\u00e9n evalu\u00f3 la citotoxicidad de estos compuestos en c\u00e9lulas de salm\u00f3n Atl\u00e1ntico, observ\u00e1ndose baja toxicidad en concentraciones bactericidas, aspecto considerado relevante para futuras aplicaciones en salud acu\u00edcola.<\/p>\n

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Los autores plantean que estos resultados posicionan a las microalgas como una fuente emergente de p\u00e9ptidos antimicrobianos para estrategias m\u00e1s sostenibles de control sanitario en acuicultura, especialmente en un contexto marcado por el aumento de la resistencia bacteriana a antibi\u00f3ticos.<\/p>\n

Revise el estudio completo aqu\u00ed<\/strong><\/a><\/h5>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Investigaci\u00f3n liderada por la PUCV identific\u00f3 p\u00e9ptidos antibacterianos derivados de microalgas con actividad contra Piscirickettsia salmonis y Vibrio anguillarum.<\/p>\n","protected":false},"author":10,"featured_media":88595,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[398],"tags":[1797,2907,477,539,447,184,2273,197],"class_list":["post-88591","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-titular","tag-antimicrobianos","tag-industria-salmonera","tag-microalgas","tag-pontificia-universidad-catolica-de-valparaiso","tag-pucv","tag-salmon","tag-salmon-chileno","tag-salmonicultura"],"yoast_head":"\nEstudio identifica p\u00e9ptidos de microalgas contra pat\u00f3genos del salm\u00f3n - Mundoacuicola<\/title>\n<meta name=\"description\" content=\"Investigaci\u00f3n identific\u00f3 p\u00e9ptidos derivados de microalgas con actividad contra Piscirickettsia salmonis y Vibrio anguillarum.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.mundoacuicola.cl\/new\/estudio-identifica-peptidos-de-microalgas-contra-patogenos-del-salmon\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Estudio identifica p\u00e9ptidos de microalgas contra pat\u00f3genos del salm\u00f3n - 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